Best Hotels on Duval St in Key West FL

We checked thousands of reviews on and to find the best hotels for your stay
Go to Hotel List View map

Nestled in the southernmost point of the United States lies the vibrant island paradise of Key West for its laid-back atmosphere, stunning beaches, and bustling nightlife, this charming destination has something to offer every type of traveler. For those seeking a truly immersive experience, staying at one of the hotels on Duval St in Key West FL is an absolute must. With its prime location in the very heart of the action, Duval Street boasts a myriad of accommodation options ranging from boutique hotels to luxury resorts, ensuring a stay that is both convenient and memorable.

As you stroll down the iconic Duval Street, lined with historic buildings and colorful storefronts, you'll find yourself immersed in the lively energy that defines Key West. Whether you're looking for a cozy bed and breakfast or a stylish boutique hotel, Duval St has an array of choices to suit every preference and budget. From the vibrant nightlife to the quaint cafes and art galleries that dot the bustling street, the hotels on Duval St in Key West FL provide a perfect home base for exploring all that this enchanting island has to offer.

Immerse yourself in the rich history and vibrant culture of Key West by choosing one of the hotels on Duval St as your accommodation. Wake up to the soothing sound of the ocean, venture out to explore the picturesque sights, and return to the comfort of your hotel for a serene evening under the starlit sky. With its unbeatable location and warm hospitality, Duval Street in Key West FL offers a unique and unforgettable experience for travelers seeking both relaxation and excitement.

Show more + Show less -

Our Top 7

(Sorted by rating & number of reviews)

1. Southernmost House Hotel (Adults Only)
2. The Reach Key West, Curio Collection By Hilton Hotel
3. Parrot Key Hotel & Villas
4. Marreros Guest Mansion - Adult Only Bed & Breakfast
5. The Gardens Hotel
6. The Artist House Bed & Breakfast
7. Ocean Key Resort & Spa, A Noble House Resort

Boutique Hotels on Duval St in Key West FL

Check Availability

Key West
Jan 02, 2026 - Jan 03, 2026

Southernmost House Hotel (Adults Only)

8.6

Good

(551 Reviews)

+ 364 photos
Perched at the southernmost point of Duval Street, The Southernmost House is a grand Victorian mansion that captures the essence of Key West's bygone era. This historic hotel features elegantly appointed rooms, panoramic ocean views, and a distinctive architectural style that reflects the island's unique history. Guests can enjoy a leisurely breakfast on the veranda, relax in the tropical gardens, and immerse themselves in the timeless charm of Key West at The Southernmost House. With its rich heritage and luxurious amenities, this iconic hotel offers a truly unforgettable stay in the very heart of Key West.
Address: 1400 Duval Street
Rating: Good 8.6 (551 Reviews)
Rooms: 18
Price: From 450$

The Reach Key West, Curio Collection By Hilton Hotel

7.2

Good

(338 Reviews)

+ 137 photos
Located on the picturesque shores of Key West by Hilton, is a beacon of luxury along Duval Street. This upscale hotel offers spacious rooms and suites with contemporary furnishings, breathtaking ocean views, and upscale amenities. Guests can unwind by the infinity pool, indulge in gourmet dining at the on-site restaurant, and enjoy direct access to the private beach for a truly exclusive experience. The Reach Key West seamlessly combines sophisticated elegance with the laid-back charm of Key West, making it a top choice for luxury travelers.
Address: 1435 Simonton Street
Rating: Good 7.2 (338 Reviews)
Rooms: 150
Price: From 347$

Luxury Hotels on Duval St in Key West FL

For travelers seeking a lavish and indulgent retreat in Key West, the luxury hotels on Duval St offer a truly exceptional experience. These opulent accommodations boast world-class amenities, stunning ocean views, and impeccable service that cater to the most discerning guests. From elegant suites to private beach access, each luxury hotel on Duval St in Key West FL provides a sumptuous escape in the midst of this tropical paradise. Immerse yourself in the lap of luxury and elevate your Key West getaway with a stay at one of these exquisite properties.

Parrot Key Hotel & Villas

8.3

Good

(2273 Reviews)

+ 247 photos
Tucked away in a secluded enclave on Duval St, Parrot Key Hotel & Villas offers spacious accommodations and a laid-back vibe that is perfect for families. The resort features colorful villas with multiple bedrooms, full kitchens, and private terraces, providing ample space for families to spread out and unwind. Guests can enjoy the four sparkling swimming pools, complimentary shuttle to Old Town Key West, and easy access to nearby beaches for a fun-filled family vacation. With its relaxed atmosphere and family-friendly amenities, Parrot Key Hotel & Villas guarantees a memorable stay for guests of all ages.
Address: 2801 North Roosevelt Boulevard
Rating: Good 8.3 (2273 Reviews)
Rooms: 148
Price: From 419$

Marreros Guest Mansion - Adult Only Bed & Breakfast

9.3

Good

(142 Reviews)

+ 146 photos
Marrero's Guest Mansion, a historic gem on Duval St in Key West FL, captures the essence of Key West's rich heritage and warm hospitality. This boutique hotel features elegantly appointed rooms that blend vintage charm with modern comfort, creating a cozy and inviting atmosphere for guests. With its lush tropical gardens, verandas with rocking chairs, and personalized service, Marrero's Guest Mansion offers a truly authentic Key West experience. Guests can enjoy a leisurely stroll along Duval Street, explore nearby attractions, and immerse themselves in the island's vibrant culture.
Address: 410 Fleming Street
Rating: Good 9.3 (142 Reviews)
Rooms: 12
Price: From 235$

Historic Hotels on Duval St in Key West FL

Enriched with a storied past and timeless charm, the historic hotels on Duval St in Key West FL offer a glimpse into the island's rich heritage. From restored mansions to boutique inns, these accommodations blend old-world elegance with modern comforts, creating a nostalgic retreat for history buffs and culture enthusiasts. Immerse yourself in the allure of Key West's past and experience the unique ambiance of these charming historic hotels on Duval St .

The Gardens Hotel

9.6

Good

(142 Reviews)

+ 158 photos
Step into a world of serenity and seclusion at The Gardens Hotel, a hidden gem nestled on Duval St in Key West FL. Surrounded by lush foliage and peaceful courtyards, this boutique hotel exudes a sense of tropical paradise. The beautifully appointed rooms and suites at The Gardens Hotel offer a luxurious retreat, complete with modern amenities and bespoke furnishings. Guests can unwind in the tranquil ambiance, enjoy complimentary breakfast in the stunning garden setting, and experience the ultimate relaxation in this exquisite Key West haven.
Address: 526 Angela Street
Rating: Good 9.6 (142 Reviews)
Rooms: 22
Price: From 539$

The Artist House Bed & Breakfast

9.1

Good

(139 Reviews)

+ 92 photos
Originally built in 1898, The Artist House stands as a historic landmark on Duval St, exuding old-world charm and artistic flair. This intimate bed and breakfast boasts individually decorated rooms, antique furnishings, and a serene courtyard garden for guests to relax and unwind. With its proximity to famous attractions like the Ernest Hemingway Home and Museum, The Artist House offers a truly immersive experience of Key West's cultural heritage. Step back in time and savor the authentic ambiance of Key West at this charming historic hotel on Duval Street.
Address: 534 Easton Street
Rating: Good 9.1 (139 Reviews)
Rooms: 8
Price: From 561$

Family-Friendly Hotels on Duval St in Key West FL

For families looking to create lasting memories in Key West, the family-friendly hotels on Duval St provide a perfect blend of comfort and convenience. With spacious accommodations, kid-friendly amenities, and proximity to popular attractions, these hotels cater to the needs of guests of all ages. From engaging activities for children to relaxing poolside lounges for parents, the family-friendly hotels on Duval St in Key West FL offer a welcoming atmosphere for families to unwind and bond in this tropical paradise.

Ocean Key Resort & Spa, A Noble House Resort

8.4

Good

(143 Reviews)

+ 327 photos
Perched at the edge of the azure waters of the Gulf of Mexico, Ocean Key Resort & Spa is a premier luxury hotel on Duval St in Key West FL. Boasting lavish accommodations, spectacular sunset views, and a full-service spa, this resort offers a haven of relaxation and indulgence. The spacious suites at Ocean Key feature upscale amenities, private balconies, and elegant decor, creating a serene retreat for guests to unwind and rejuvenate. With its prime location overlooking Mallory Square, Ocean Key Resort & Spa embodies the essence of luxury living in Key West.
Address: Zero Duval Street
Rating: Good 8.4 (143 Reviews)
Rooms: 100
Price: From 904$